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72. Schmitz, S., Cherny, S.S., & Fulker, D.F. (1998). Increase in power through multivariate analyses. Behavior Genetics, 28, 357-363.Power to detect genetic and environmental influences increases not only
with sample size but also with the number of measurements through longitudinal
and/or multivariate designs, if those measures correlate with each other.
Power simulations are presented for uni- through quadrivariate cases,
with differing genetic and environmental parameters. Even though subject
attrition is a problem for most longitudinal studies, the gain in power
available may more than make up for this shortcoming in many situations.
In terms of planning studies to examine genetic and environmental influences,
power calculations should not only consider sample size but number of
measurements on particular phenotypes and their intercorrelations. |