Testing evolutionary hypotheses using human genetic data, and modeling and simulating genetically informative designs that better enable us to understand the causes of human differences.
Relevant Work:
Keller, M. C., Visscher, P. M., & Goddard, M. E. (2011).
Quantification of inbreeding due to distant ancestors and its
detection using dense SNP data. Genetics, 189, 237-249 PMCID: PMC3176119
Duncan, L. E. & Keller, M. C. (2011). A critical review of the first
ten years of candidate gene-by-environment interaction research in
psychiatry. American Journal of Psychiatry, 168, 1041-1049. PMID:
21890791
Keller, M. C., Medland, S. E., & Duncan, L. E. (2010). Are extended
twin family designs worth the trouble? A comparison of the bias,
precision, and accuracy of parameters estimated in four twin family
models. Behavior Genetics, 40, 377-393. [Fulker Award winner, best
paper published in Behavioral Genetics, 2010]. PMID:
20013306
Keller, M. C., & Miller, G. F. (2006). Resolving the paradox of
common, harmful, heritable mental disorders: Which evolutionary
genetic models work best? Behavioral and Brain Sciences, 29, 385-452. PMID:
17094843