447 UCB
Boulder, CO 80309-0345
phone: 303-492-9677
fax: 303-492-8063
email:
Michael.Marks@Colorado.edu
Genetic influences on molecular, biochemical, physiological, and behavioral factors mediating the responses to nicotine in mice.
1. Gotti C, Moretti M, Meinerz NM, Clementi F, Gaimarri A, Collins AC, Marks
MJ (2008) Partial deletion of the nicotinic cholinergic receptor alpha 4
or beta 2 subunit genes changes the acetylcholine sensitivity of
receptor-mediated 86Rb+ efflux in cortex and thalamus and alters relative
expression of alpha 4 and beta 2 subunits. Mol Pharmacol 73:1796-807.
PMID: 18337473 | pubmed abstract |
2.
Marks MJ, Meinerz NM, Drago J, Collins AC.(2007).
Gene targeting demonstrates that alpha4 nicotinic acetylcholine receptor subunits contribute to expression of diverse [3H]epibatidine binding sites and components of biphasic 86Rb+ efflux with high and low sensitivity to stimulation by acetylcholine.
Neuropharmacology., 53(3), 390-405.
PMID: 17631923 | pubmed abstract |
3. Marks MJ, Whiteaker P, Collins AC. (2006).
Deletion of the alpha7, beta2, or beta4 nicotinic receptor subunit genes identifies highly expressed subtypes with relatively low affinity for [3H]epibatidine.
Mol Pharmacol., 70(3), 947-59.
PMID: 16728647 | pubmed abstract |
Recent Publications