Study of mechanisms involved in nicotine addiction in association with nicotinic receptor expression and function, using a model of drug self-administration in mice.
Selected Publications:
1. Zambrano CA, Marks MJ, Cassels BK, Maccioni RB. (2009). In vivo effects of 3-iodocytisine: Pharmacological and genetic analysis of hypothermia and evaluation of chronic treatment on nicotinic binding sites. Neuropharmacology. PMID: 19481555
2. Zambrano CA, Egaña JT, Núñez MT, Maccioni RB, González-Billault C. (2004). Oxidative stress promotes tau dephosphorylation in neuronal cells: the roles of cdk5 and PP1. Free Radic Biol Med. 2004 Jun 1;36(11):1393-402.
PMID: 15135175