The 100 most significant genes in long-lived mutants
P function                    
3.4167E-07  
3.65949E-06 Protein of unknown function, has strong similarity to C. elegans Y55B1B_119.C
4.98193E-06 GTP-binding protein of the ras superfamily, putative ortholog of S. cerevisiae Yal048p
7.09114E-06 Protein of unknown function
8.76745E-06 GTP-binding protein of the ras superfamily, has similarity to arf family members of S. cerevisiae and human
1.80176E-05 Member of the cysteine protease protein family
1.80416E-05 Yolk proteins yp115 and yp88
1.82493E-05 Protein with strong similarity to C. elegans T20B6.2
2.04507E-05 Putative beta-adaptin
2.58881E-05 Putative ortholog of S. cerevisiae Mlh1p, a mismatch repair protein
2.84953E-05 Ankyrin repeat-containing protein with similarity to C. elegans UNC-44 and human and D. melanogaster ankyrins
2.97043E-05 Member of the phosphofructokinase protein family
3.24578E-05 Member of the MCM initiator complex (DNA replication) protein family
4.57716E-05 Putative coiled-coil protein, has strong similarity to S. cerevisiae Rhc18p, involved in recombinational DNA repair
4.64486E-05 Protein with weak similarity to C. elegans T06D10.2 gene product
4.78729E-05 Putative ER chaperone (GenBank), has strong similarity to H. sapeins ORP150 gene product [oxygen-regulated protein]
5.26568E-05 Member of the EGF-repeat protein family
5.5003E-05  
6.16005E-05 Putative paralog of C. elegans F26H9.8, has strong similarity to Human HUGT1, UDP-glucose-glycoprotein glucosyltransferase
6.36326E-05 Lactate dehydrogenase
7.2762E-05 Protein of unknown function, has weak similarity to C. elegans R102.1
7.32497E-05 Protein of unknown function
7.99388E-05 Protein of unknown function
8.52605E-05 Transcription factor required for early embryogenesis
8.97424E-05 Actin
9.30816E-05 Protein of unknown function
9.81737E-05 Member of the carboxypeptidase protein family
0.000111879 Protein with similarity to human and Drosophila propionyl-coenzyme A carboxylases
0.00012295 Member of a protein family
0.000123352 Protein with similarity to human placental protein DIFF33
0.000124118 Member of the heat shock HSP16-1 protein family
0.000127629 Protein with a region of strong similarity to human ZYG homologue (Hs.29285, isolated from testis), member of the C. elegans zyg-11 like protein family
0.000128286 Protein with strong similarity to human CKAP1, a cytoskeleton-associated protein, containing a CAP-GLY domain
0.000129654 Protein of unknown function
0.000140784 Member of the glycogen phosphorylase protein family
0.00014288  
0.000157919 Protein with strong similarity to a region of C. elegans F14D2.9, a putative tyrosine protein phosphatase
0.000165658 Probable aspartyl protease and an ortholog of human cathepsin D
0.000168696 Member of the aspartate amino transferase protein family
0.000176298 Protein of unknown function
0.000185816  
0.000189435 Protein of unknown function, putative paralog of C. elegans C28A5.1
0.000196838 Cytoplasmic zinc-finger protein involved in regulation of early morphogenesis
0.000198568 Protein of unknown function
0.000203693 Protein of unknown function, has weak similarity to C. elegans ZK678.4
0.000204528 Delta5-fatty acid desaturase; has strong similarity to H. sapiens Hs.132898 gene product
0.000205234 Putative transmembrane protein with similarity over C-terminal half to D. melanogaster innexins OGRE and SHAKING-B and to a number of C. elegans members of the OPUS/innexin protein family
0.000210589 Protein of unknown function
0.000212673 No description
0.000228042 Member of the mitochondrial carrier (MCF) protein family
0.000229058 S-adenosylmethionine decarboxylase
0.000233382 Protein of unknown function
0.00023493 Ladder protein
0.000243197 Protein of unknown function, has similarity to an uncharacterized C. elegans protein family including F58E6.4
0.000254252 Protein of unknown function, putative paralog of C. elegans F57F4.3
0.000267705 No description
0.000271137 Protein of unknown function, has strong similarity to human KIAA0645 protein (Hs.155987, isolated from a brain cDNA library)
0.000274586 Protein of unknown function, has weak similarity to C. elegans ZK596.1
0.000286691 Member of the pyruvate kinase protein family
0.000291599 Member of the MCM initiator complex (DNA replication) protein family
0.00029298 Protein containing a zinc finger domain, putative paralog of C. elegans C09G9.6, has strong similarity to C. elegans F32A11.6
0.000303218 Putative tubulin-specific chaperone, has strong similarity to human TBCE (tubulin-specific chaperone E), has similarity to S. cerevisiae Pac2p
0.000303967 Protein with similarity to the N-terminus of S. cerevisiae Ypl217p, a protein of unknown function
0.000311915 Putative methyltransferase, putative ortholog of human METTL1 and S. cerevisiae Ydl201p
0.000320151 Member of the collagen triple helix repeat (20 Copies) protein family
0.000321753 Protein of unknown function
0.000333441 Member of an uncharacterized protein family
0.000335698 Protein of unknown function
0.000347561 Protein of unknown function
0.000349256 Putative bZIP transcription factor
0.000349714 Member of the vitellogenin protein family
0.000359592 Protein of unknown function
0.000370795  
0.0003803 Member of the pumilio family of RNA binding domain proteins, putative paralog of C. elegans B0273.2 and F18A11.1
0.00038457 Putative A-type regulatory subunit for serine/threonine phosphatase 2A
0.000384899 Protein with moderate similarity to C. elegans T03D3.5 gene product
0.000386845 Protein with strong similarity to D. melanogaster RGA (Regena) protein
0.000388409  
0.000396256 Member of the C-type lectin protein family
0.000400224 Protein with strong similarity to polyphosphoinositide phosphatases
0.000405459 Protein with moderate similarity to S. cerevisiae YKL100C
0.000411907 Leucine-rich repeat domain protein with strong similarity to human Hs.76689, an acidic nuclear phosphoprotein involved in oncogenesis; probable paralog of C. elegans T19H12.2
0.000412076 Member of the actin and actin-related protein family
0.000418002 Protein with weak similarity to H. sapiens Hs.12413 (Human mRNA for KIAA0191 gene, partial cds)
0.000419124 Probable small nuclear ribonucleoprotein (snRNP) D2 polypeptide
0.000427928 Protein of unknown function, has weak similarity to S. cerevisiae WD-40 repeat protein Ydr324p
0.000428486 Member of the protease protein family
0.000432755  
0.000443723 Protein of unknown function
0.000447729 Protein with moderate similarity to C. elegans W07B3.2
0.00045207 Putative transmembrane protein, contains ten predicted transmembrane domains
0.000455031 Part of the class B pathway that antagonizes vulval induction, member of the zinc finger, C2H2 type protein family
0.000464197 Calmodulin
0.000468535 Protein with similarity to mitochondrial processing peptidases of human and C. elegans, has similarity to human ubiquinol-cytochrome c reductases UQCRC2 and UQCRC1
0.000475623  
0.000487966 Protein contains a putative RhoGAP domain, has similarity to human Hs.21264 protein, mRNA for KIAA0782 protein, isolated from a brain cDNA library
0.000512623 Putative coiled-coil protein of the SMC (structural maintenance of chromosomes) protein family, involved in mitosis and X chromosome dosage compensation, probable ortholog of S. cerevisiae Smc2p
0.000513791 Protein of unknown function
0.000520092 Protein of unknown function, has weak similarity to human protein KIAA0648 (Hs.31921)