The next workshop will be held in Boulder, Colorado, March 5-9, 2001, with John Hewitt as local host. Some of the application programming will be based on the package, Mx, developed by Dr. Mike Neale for the flexible analysis of genetically-informative data. The Mx home page is at http://griffin.vcu.edu/mx.
This advanced course is intended for those who have attended earlier workshops and who are already familiar with the statistical and genetic principles of univariate and simple multivariate analyses with sibling data, who are familiar with the Mx program, and who have an interest in QTL analysis in the context of twin and sibling data.
The registration fee will be $300.00, payable by January 12, 2001 Accommodations are being reserved at the Regal Harvest House, Boulder. Details of local arrangements, registration, and accommodation are available from the workshop assistant, Shirley Stearns. A home page is on the World Wide Web at http://ibgwww.colorado.edu/twins2001.
The provisional faculty roster includes:
| L. Eaves, H. Maes & M. Neale | Richmond, VA, USA | A. Heath, J. Rice | St. Louis, MO, USA | N. Martin | Brisbane, Queensland, Australia | D. Boomsma, C. van Baal & C. Dolan | Amsterdam, The Netherlands | P. Sham | London, UK | L. Cardon [Academic Director], S. Cherny & G. Abecasis | Oxford, UK | J. Hewitt & J. Lessem | Boulder, CO, USA | C. Amos | Houston, TX |
The course will include: Use of twins in genetic analysis; likelihood models; familial resemblance; basic principles of segregation analysis; basic principles of linkage analysis; identity by descent (IBD) and genetic covariance; estimating IBD from marker data; sib-pair methods for QTL linkage analysis, linkage analysis in selected samples; power for linkage analysis; multivariate analysis; association studies-principles, population studies, family studies, power; linkage disequilibrium; power and Type 1 error in multiple testing. Hands-on analysis will employ networked terminals.
An application form can be printed from http://ibgwww.colorado.edu/twins2001/registration.html. Further information may be obtained from John Hewitt, or the workshop assistant, Shirley Stearns, IBG, University of Colorado, Boulder, CO 80309-0447, USA; Telephone: 303-492-2831; FAX: 303-492-8063; E-mail: John.Hewitt@Colorado.edu or Shirley.Stearns@Colorado.edu