***** indicates some introductory material of special relevance to the workshop
Papers
Abecasis GR, Cardon L, Cookson WOC, A general test of association for quantitative traits in nuclear families, Am J Hum Genet, 66, 279-292, 2000
Abecasis GR, Cardon LR, Cookson WO, Sham PC, Cherny SS. Association analysis in a variance components framework. Genet Epidemiol. 21 Suppl 1:S341-6, 2001
Abecasis GR, Cookson WO, Cardon LR. (2001) The power to detect linkage disequilibrium with quantitative traits in selected samples. Am J Hum Genet., 68(6):1463-74.
Allison, D.B., Neale M.C. (2002) Joint tests of linkage and association for quantitative traits. Theoretical Population Biology, 60, 239-51.
Boomsma DI, Using multivariate genetic modeling to detect pleiotropic quantitative trait loci, Behavior Genetics, 26, 161-166, 1996
Boomsma D.I. and Dolan C.V., A comparison of power to detect a QTL in sib-pair data using multivariate phenotypes, mean phenotypes, and factor-scores, Behav Genet, 28, 329-340, 1998
Boomsma DI, Dolan CV, Multivariate QTL analysis using structural equation modeling: A look at power under simple conditions, in: Advances in Twin & Sib-Pair Analysis, T Spector, H Snieder, A MacGregor (Eds), 203-218, Greenwich Medical Media Ltd, 2000
***** Boomsma DI, Busjahn A, Peltonen L, The classical twin study and beyond. Nat Genet Rev. 2002, 3, 872-882
Cardon L.R. and Fulker D.W., The power of interval mapping of quantitative trait loci using selected sib pairs, Am J Hum Genet, 55, 825-833, 1994
***** Cardon, L. Abecasis, G.R., Some properties of a variance components model for fine-mapping quantitative trait loci, Behavior Genetics, 30, 2000
***** Cardon, L.R, and Bell, JI Association study designs for complex diseases. Nat Rev Genet. 2:91-9, 2001
Carey G. and Williamson J., Linkage analysis of quantitative traits: Increased power by using selected samples, Am J Hum Genet, 49, 786-796, 1991
Dolan C.V., Neale M. and Boomsma D.I., A simulation study of the effects of sib-pair selection in genetic covariance structure modeling of QTL effects, Am J Human Genetic, 64, 268-280, 1999
Dolan CV, Boomsma DI, MC Neale, A note on the power provided by sibships of size 3 and 4 in genetic covariance modeling of a codominant QTL, Behavior Genetics, 29, 163-170, 1999
Dolan C.V. and Boomsma D.I., Optimal selection of sib-pairs from random samples for linkage analysis of a QTL using the EDAC test, Behav Genet, 28, 197-206, 1998
Eaves L. and Meyer J., Locating human quantitative trait loci: Guidelines for the selection of sibling pairs for genotyping, Behav Genet, 24, 443-455, 1994
Eaves L.J., Neale M. and Maes H., Multivariate multipoint linkage analysis of quantitative trait loci, Behav Genet, 26, 519-525, 1996
Evans DM, Gillespie NA, Martin NG. Biometrical genetics. Biol Psychol. 61(1-2):33-51, 2002
Fulker D.W., Cherny S.S., and Cardon L.R., Multipoint interval mapping of quantitative trait loci, using sib pairs, Am J Hum Genet, 56, 1224-1233, 1995
Fulker D.W. and Cherny S.S., An improved multipoint sib-pair analysis of quantitative traits, Behav Genet, 26, 527-532, 1996
***** Fulker, D.W., Cherny, S.S., Sham, P.C., and Hewitt, J.K., Combined linkage and association sib-pair analysis for quantitative traits, Am J Hum Genet, 64, 259-267, 1999.
Goldgar D.E., Multipoint analysis of human quantitative genetic variation, Am J Hum Genet, 47, 957-967, 1990
Haseman J.K. and Elston R.C., The investigation of linkage between a quantitative trait and a marker locus, Behav Genet, 2, 3-19, 1972
Kruglyak L. and Lander E., Complete multipoint sib pair analysis of qualitative and quantitative traits, Am J Hum Genet, 57, 439-454, 1995
Kruglyak, L., Daly, M.J., Reeve-Daly, M.P., and Lander, E.S., Parametric and nonparametric linkage analysis: a unified approach, Am J Hum Genet, 58, 1347-1363, 1996
Lander, E. and Kruglyak, L., Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results, Nat Genet, 11, 241-247, 1995.
Martin N., Boomsma D., and Machin, G., A twin-pronged attack on complex traits, Nat Genet, 17, 387-391, 1997
Neale, M.C. (2001) The use of Mx for association and linkage analysis. Genescreen, 1: 107-111
Neale, M.C. (1998) Twin analysis. In P. Armitage, T. Colton (Eds) Encyclopedia of Biostatistics. New York: John Wiley.
Pratt SC, Daly MJ, Kruglyak L, Exact multipoint quantitative-trait analysis in pedigrees by variance components, Am J Hum Genet, 66, 1153-1157, 2000
***** Risch N. and Zhang H., Extreme discordant sib pairs for mapping quantitative trait loci in humans, Science, 268, 1584-1589, 1995
Risch NJ. Searching for genetic determinants in the new millennium. Nature. 405, 847-56, 2000
Sham PC, Purcell S, Cherny SS, Abecasis GR. Powerful regression-based quantitative-trait linkage analysis of general pedigrees. Am J Hum Genet. 71(2):238-53, 2002
Slagboom PE, Meulenbelt I. Organisation of the human genome and our tools for identifying disease genes. Biol Psychol. 61, 11-31, 2002
Teng J, Risch N. The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping. Genome Res. 1999 9(3):234-41.
Terwilliger, J. D., and Göring, H. H. H. Gene mapping in the 20th and 21st centuries: statistical methods, data analysis, and experimental design. Hum Biol, 72(1); 63-132, 2000
Van den Oord EJ, Snieder H. Including measured genotypes in statistical models to study the interplay of multiple factors affecting complex traits. Behav Genet. 32, 1-22, 2002
Van den Oord EJ. Estimating effects of latent and measured genotypes in multilevel models.
Stat Methods Med Res. 10, 393-407, 2001
***** Vink JM, Boomsma DI, Gene finding strategies, Biological Psychology, 61, 53-71, 2002
Visscher PM, Hopper JL. Power of regression and maximum likelihood methods to map QTL from sib-pair and DZ twin data. Ann Hum Genet. 65(Pt 6):583-601, 2001
Vogler G.P., Tang W., Nelson T.L., Hofer S.M., Grant J.D., Tarantino L.M., Fernandez J.R., A multivariate model for the analysis of sibship covariance structure using marker information and multiple quantitative traits, Genetic Epidemiology, 14, 921-926, 1997
Zhang W, Collins A, Abecasis GR, Cardon LR, Morton NE. Mapping quantitative effects of oligogenes by allelic association. Ann Hum Genet. 66(Pt 3):211-21, 2002
Books
Balding DJ, Bishop M, Cannings C (Eds). Handbook of Statistical Genetics. Chichester: John Wiley & Sons, Ltd. 2001
Ewens WJ, Grant GR. Statistical methods in bioinformatics. New York: Springer Verlag. 2001
***** Falconer DS, Mackay TFC, Introduction to Quantitative Genetics (4rd ed.), Longman, London, 1996
Khoury MJ, Beaty TH, Cohen BH, Fundamentals of Genetic Epidemiology, Oxford: Oxford University Press, 1993
Lange K, Mathematical and Statistical Methods for Genetic Analysis, Springer-Verlag, New-York, 1997
Lynch M, Walsh B, Genetics and Analysis of Quantitative Traits, Sinauer Associates, Inc., Sunderland, MA, 1998
Neale MC, Cardon LR, Methodology for Genetic Studies of Twins and Families (NATO ASI Series D: Behavioural and Social Sciences-Vol. 67), Kluwer Academic Publishers B.V., Dordrecht, The Netherlands, 1992
Ott, J, Analysis of Human Genetic Linkage. Revised Edition, The John Hopkins University Press, Baltimore, 1991
***** Sham P, Statistics in Human Genetics, John Wiley & Sons, New York, 1998
Sham P, Bishop M (Eds), Analysis of Multifactorial Disease. BIOS Scientific Publishers, Oxford, 2000
Spector TD, Snieder EH, MacGregor AJ (Eds), London: Greenwich Medical Media Ltd 2000
Strachan T, Read AP, Human Molecular Genetics, BIOS Scientific Publishers, Oxford, 1996
Terwilliger JD, Ott J, Handbook of Human Genetic Linkage, Baltimore: John Hopkins University Press, 1994
Thompson EA. Pedigree Analysis in Human Genetics. Baltimore: John Hopkins University Press, Baltimore, 1986
Weiss KM, Genetic Variation and Human Disease. Principles and Evolutionary Approaches, Cambridge University Press, Cambridge, 1993
See also: http://linkage.rockefeller.edu/bib/asso/