Basic Analysis QTL1 9.86 0.0017 QTL2 0.62 ----- Add siblings Total test QTL1 15.38 0.0000 QTL2 2.57 ----- Within family test QTL1 0.94 ----- QTL2 0.81 ----- Test for stratification QTL1 4.15 0.0416 QTL2 0.21 ----- Add posterior probabilities as simple covariates Total test (K=3, 3 covariates added) QTL1 0.27 ----- QTL2 0.09 ----- L-ASSOC tests Standard test QTL1 9.846 0.002 QTL2 0.617 0.432 Allow for class-differences in allele frequency QTL1 0.297 0.586 QTL2 0.093 0.760 Test for stratification QTL1 55.007 0.000 QTL2 1.861 0.394 Allow for class-differences and class X QTL interaction QTL1 0.323 0.956 QTL2 24.090 0.000 Genomic control Median LRT = 6.867 Controlled QTL1 = 9.86 / (6.867/0.456) = 0.6547 Controlled QTL2 = 0.62 / (6.867/0.456) = 0.0411