Link Lab publications
(please contact me at linkc@colorado.edu for reprint PDFs)
Link C.D. (1995) Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans. Proc Natl Acad Sci U S A 92:9368-9372.
Fay D.S., Fluet A., Johnson C.J., Link C.D. (1998) In vivo aggregation of beta-amyloid peptide variants. J Neurochem 71:1616-1625.
Yatin S.M., Varadarajan S., Link C.D., Butterfield D.A. (1999) In vitro and in vivo oxidative stress associated with Alzheimer's amyloid beta-peptide (1-42). Neurobiol Aging 20:325-330; discussion 339-342.
Link C.D., Cypser J.R., Johnson C.J., Johnson T.E. (1999) Direct observation of stress response in Caenorhabditis elegans using a reporter transgene. Cell Stress Chaperones 4:235-242.
Butterfield D.A., Yatin S.M., Link C.D. (1999) In vitro and in vivo protein oxidation induced by Alzheimer's disease amyloid beta-peptide (1-42). Ann N Y Acad Sci 893:265-268.
Link C.D., Johnson C.J., Fonte V., Paupard M., Hall D.H., Styren S., Mathis C.A., Klunk W.E. (2001) Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34. Neurobiol Aging 22:217-226.
Link C.D. (2001) Transgenic invertebrate models of age-associated neurodegenerative diseases. Mech Ageing Dev 122:1639-1649.
Link C.D., Johnson C.J. (2002) Reporter transgenes for study of oxidant stress in Caenorhabditis elegans. Methods Enzymol 353:497-505.
GuhaThakurta D., Palomar L., Stormo G.D., Tedesco P., Johnson T.E., Walker D.W., Lithgow G., Kim S., Link C.D. (2002) Identification of a novel cis-regulatory element involved in the heat shock response in Caenorhabditis elegans using microarray gene expression and computational methods. Genome Res 12:701-712.
Fonte V., Kapulkin V., Taft A., Fluet A., Friedman D., Link C.D. (2002) Interaction of intracellular beta amyloid peptide with chaperone proteins. Proc Natl Acad Sci U S A 99:9439-9444.
Blumenthal T., Evans D., Link C.D., Guffanti A., Lawson D., Thierry-Mieg J., Thierry-Mieg D., Chiu W.L., Duke K., Kiraly M., Kim S.K. (2002) A global analysis of Caenorhabditis elegans operons. Nature 417:851-854.
Strayer A., Wu Z., Christen Y., Link C.D., Luo Y. (2003) Expression of the small heat-shock protein Hsp16-2 in Caenorhabditis elegans is suppressed by Ginkgo biloba extract EGb 761. Faseb J 17:2305-2307.
Link C.D., Taft A., Kapulkin V., Duke K., Kim S., Fei Q., Wood D.E., Sahagan B.G. (2003) Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model. Neurobiol Aging 24:397-413.
Kampkotter A., Volkmann T.E., de Castro S.H., Leiers B., Klotz L.O., Johnson T.E., Link C.D., Henkle-Duhrsen K. (2003) Functional analysis of the glutathione S-transferase 3 from Onchocerca volvulus (Ov-GST-3): a parasite GST confers increased resistance to oxidative stress in Caenorhabditis elegans. J Mol Biol 325:25-37.
Drake J., Link C.D., Butterfield D.A. (2003) Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model. Neurobiol Aging 24:415-420.
Link C. D. (2005) Invertebrate Models of Azheimer's Disease. Genes, Brain and Behavior 4(3):147-56.
Kapulkin V., Hiester B.G., Link C. D. (2005) Compensatory regulation among ER chaperones in C. elegans. FEBS Lett. May 19, 2005