Genetics of Substance Use Disorders
PSYCH 7102: Concepts in Behavioral Genetics
Instructor: Dr. Michael Stallings
Phone: 2-2826
Email: Michael.Stallings@Colorado.Edu
Course Description
This graduate-level course will be presented in a seminar format. Each class session a student will be assigned to lead the discussion of an important current paper in the topic area assigned by the instructor. This will be followed by general discussion/lecture by the instructor or a guest lecturer on related material.Topics will include the epidemiology, clinical aspects, neurobiology and etiology of substance abuse and dependence. There will be a focus on nicotine, alcohol, marijuana, opioids, and stimulants including cocaine. However, additional topics will include polysubstance abuse, comorbid psychopathology, and developmental and gender issues. Course evaluations will be based on class participation and a term paper (10-20 page paper on a topic approved by the instructor).
Syllabus
|
Date
|
Topic
|
Readings
|
| Jan 17 | Course Introduction | |
| Jan 22 | Nicotine: Epidemiology/Clinical Aspects | *Koopmans et al., 1999; Pomerleau et al., 1993 |
| Jan 29 | Nicotine: Neurobiology | *Lerman & Niaura, 2002; Madden et al., 1999 |
| Feb 05 | Nicotine Dependence: Etiology | *Heath et
al., 1993; *Straub et al., 1999; Kendler et al., 1999; McGue chapter |
| Feb 12 | Alcohol: Epidemiology/Clinical Aspects | *Schuckit, 1994a; 1994b; Schuckit et al., 2001 |
| Feb 19 | Alcohol: Neurobiology | *Noble et al., 2000; Faroud & Li, 1999 |
| Feb 26 | Alcohol Dependence: Etiology | * Heath et
al., 1993; Reich et al., 1998; Kendler et al., 1992 |
| Mar 05 | Methodology Workshop (No Class) | |
| Mar 12 | Illicit Drugs: Neurobiology | *Tsuang et al., 1998; Maes et al., 1999 |
| Mar 19 | Illicit Drugs: Etiology | *Kendler
& Prescott, 1998; McGue et al., 2000; Uhl et al., 2001; Kendler et al., 2000 |
| Mar 26 | Spring Break! (No Class) | |
| Apr 02 | Polysubstance Abuse | *Koob & Le Moal, 2000; De Fiebre & Collins, 1993 |
| Apr 09 | Comorbid Psychopathology | *Kreuger et
al., 2002; Cadoret et al., 1987; (Antisocial Behavior, Gambling, Risky Sex) Slutske; Young et al., 2000 |
| Apr 16 | Personality and Substance Use Disorders | *Wills et
al., 1994; Cloninger, 1987; Heath et al., 1995 |
| Apr 23 | Brain Reward Mechanisms | Gardner Chapter |
| Apr 30 | Treatment Issues (Term Paper Due) |
