Identification of genetic mechanisms contributing to alcohol abuse and smoking behaviors, particularly the role of neuronal nicotinic acetylcholine receptors.
Selected Publications:
1.
Hoft NR, Corley RP, McQueen MB, Schlaepfer IR, Huizinga D, Ehringer MA. (2009).Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample.
Neuropsychopharmacology, 34(3), 698-706.
PMID: 18704094
2.
Schlaepfer IR, Hoft NR, Collins AC, Corley RP, Hewitt JK, Hopfer CJ, Lessem JM, McQueen MB, Rhee SH, Ehringer MA. (2008).
The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults.
Biol Psychiatry., 63(11), 1039-46.
PMID: 18163978