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The models described in this section are appropriate for analyzing
G E interaction when genes and environment are acting
independently. However, if there is genotype - environment
correlation, then more sophisticated statistical procedures are
necessary for the analysis. One way of detecting a G - E
correlation is to compute the cross-correlations between one twin's
environment and the trait of interest in the cotwin
(Heath et al., 1989b).
If the cross-correlation is not significant, there is no evidence for
a G - E correlation, and the G E analysis may
proceed using the methods described below.
1 Models for G E Interactions