ANNOUNCEMENT


THE SIXTEENTH INTERNATIONAL WORKSHOP ON METHODOLOGY OF TWIN AND FAMILY STUDIES:

THE ADVANCED COURSE MARCH 3TH – MARCH 7TH, 2003.


The next workshop will be held in Boulder, Colorado, March 3-7, 2003, with John Hewitt as local host. The application programming will be based on the package, Mx, for the flexible analysis of nuclear family data, QTDT and Merlin for efficient linkage and association analysis of pedigree data, the Genetic Power Calculator (GPC) and others for specific genetic problems. See http://griffin.vcu.edu/mx, http://bioinformatics.well.ox.ac.uk/Merlin and http://statgen.iop.kcl.ac.uk/gpc for background program information.


This advanced course is intended for those who have attended earlier workshops and who are already familiar with the statistical and genetic principles of univariate and simple multivariate analyses with sibling data, who are familiar with the Mx program, and who have an interest in QTL analysis in the context of twin and sibling data.


The registration fee will be $300.00, payable by January 17, 2003. Accommodations are being reserved at the Millenium Harvest House, Boulder. Details of local arrangements, registration, and accommodation are available from the workshop secretary, Kendra Locher.


A home page is on the World Wide Web at http://ibgwww.colorado.edu/workshop2003.


The provisional faculty roster includes:

H. Maes & M. Neale Richmond, VA, USA

A. Heath St. Louis, MO, USA

N. Martin Brisbane, Queensland, Australia

D. Boomsma & C. van Baal Amsterdam, The Netherlands

P. Sham, S. Purcell London, UK

L. Cardon [Academic Director] & S. Cherny Oxford, UK

G. Abecasis Ann Arbor, MI, USA

J. Hewitt & J. Lessem Boulder, CO, USA

The course will include: Use of twins in genetic analysis; likelihood models; familial resemblance; basic principles of segregation analysis; basic principles of linkage analysis; identity by descent (IBD) and genetic covariance; estimating IBD from marker data; sib-pair methods for QTL linkage analysis, linkage analysis in selected samples; power for linkage analysis; multivariate analysis; association studies-principles, population studies, family studies, power; linkage disequilibrium; power and Type 1 error in multiple testing. Hands-on analysis will employ networked terminals.


An application form can be printed from

http://ibgwww.colorado.edu/workshop2003/registration.html. Further information may be obtained from John Hewitt, or the workshop secretary, Kendra Locher, IBG, University of Colorado, Boulder, CO 80309-0447, USA; Telephone: 303-735-5440; FAX: 303-492-8063; E-mail: John.Hewitt@Colorado.edu or Kendra.Locher@Colorado.edu


Minority students and scientists are especially encouraged to attend. Partial financial support for US minority participants is available by application to the local host, John Hewitt.


Financial support for this workshop is provided by grant MH19918 from the National Institute of Mental Health.


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