Worm gerontogenes

List of gerontogenes found in the nematode-worm Caenorhabditis elegans

view the list in PDF format

black = published, red = unpublished
gene chromosome life span/WT Longevity reference Comment
age-1 II 1.6 Klass 1983 abstract, Friedman & Johnson 1988 abstract
age-2 I 1.2 Yang and Wilson, 1999 abstract longer-lived at higher temperature
age-n     Keightley et al., 2000 abstract
age-n(a)     2000 East Coast C. elegans Meeting abstract 136 suppressor of daf-16 shortivity
age-n(b)     2000 East Coast C. elegans Meeting abstract 136 suppressor of daf-16 shortivity
che-2 X 1.4 Apfeld & Kenyon 1999 abstract
che-3 I 2 Apfeld & Kenyon 1999 abstract
che-11 V 1.4 Apfeld & Kenyon 1999 abstract
che-13 I 1.3 Apfeld & Kenyon 1999 abstract
clk-1 III 1.4 Lakowski & Hekimi 1996 abstract
clk-2 III 1.1 Lakowski & Hekimi 1996 abstract
clk-3 II 1.2 Lakowski & Hekimi 1996 abstract
ctl-1 II   Taub et al., 1999 abstract required for age-1 Age but not for twp-1 Age
daf-2 III 2 Kenyon 1993 abstract
daf-5 II   2000 East Coast C. elegans Meeting abstract 43 only one allele was Age
daf-6 X 1.3 Apfeld & Kenyon 1999 abstract
daf-10 IV 1.6 Apfeld & Kenyon 1999 abstract
daf-12;daf-2 X 3.4 Larsen et al., 1995 abstract strongly allele-specific
daf-19 II 1.3 Apfeld & Kenyon 1999 abstract SOMEONE is doing chip work on daf-19
daf-21[hsp90] V 1.5 1999 International C. elegans Meeting abstract 524 hsp90
daf-28 V 1.1 Malone et al., 1996 abstract
des-1   1.6 Herndon & Driscoll, 2000 (no abstract available)
eat-1 IV 1.3 Lakowski and Hekimi 1998 abstract
eat-2 II 1.4 Lakowski and Hekimi 1998 abstract
eat-6 V 1.4 Lakowski and Hekimi 1998 abstract
eat-13 X 1.3 Lakowski and Hekimi 1998 abstract
eat-18 I 1.4 Lakowski and Hekimi 1998 abstract
efk-1 III 1.25 1999 International C. elegans Meeting abstract 830 Elongation Factor 2 Kinase homolog
gro-1 IV 1.2 Lakowski & Hekimi 1996 abstract
ins-18 1 ~1.2 Kawano et al., 2000 abstract T28B8.3 (authors also use "Ceinsulin-1")
itt-n(a)     Walker et al., 1998a,b abstract
itt-n(b)     Walker et al., 1998a,b abstract
itt-n/HG25   1.2 Yang and Wilson, 2000 abstract
itt-n/HG96   1.5 Yang and Wilson, 2000 abstract
itt-n/HG246   1.3 Yang and Wilson, 2000 abstract
mec-8 I 1.6 Apfeld & Kenyon 1999 abstract
old-1 II 2 Murakami and Johnson 1998 abstract
osm-1 X 1.4 Apfeld & Kenyon 1999 abstract
osm-3 IV 1.6 Apfeld & Kenyon 1999 abstract
osm-5 X 2.2 Apfeld & Kenyon 1999 abstract
osm-6 V 1.6 Apfeld & Kenyon 1999 abstract
pdk-1 X 1.6 Paradis et al., 1999 abstract Daf-c
rad-8 I 1.3 Ishii et al., 1994 abstract Only at 16oC
spe-10 V 1.4 Cypser and Johnson, 1999 abstract
spe-26 IV 1.6 Van Voorhies 1992 abstract Supressible by daf-16, but no known Daf
tax-4 III 1.9 Apfeld & Kenyon 1999 abstract
unc-4 II 4 Gems et al., 2000 abstract male-specific, but JC finds herms strongly Itt
unc-13 I 2.9 Gems et al., 2000 abstract male-specific
unc-26 IV 1.5 Lakowski and Hekimi 1998 abstract Eat phenotype
unc-31 IV 1.3 Ailon et al., 1999 abstract Daf-c
unc-32 III 2.8 Gems et al., 2000 abstract male-specific
unc-64 III 1.8,2.4 Ailon et al., 1999 abstract, Gems et al., 2000 abstract NOT male-specific
unc-76 V 1.4 Gems et al., 2000 abstract male-specific

 

Back to WORM page

Mouse People Publications Links Home