Molecular Genetics Core C:
The Molecular Genetics Core is responsible for extracting DNA from samples
obtained by Components I, II, III, and IV, for storing the extracted DNA
for the duration of the center, and for genotyping samples for specified
individuals as required by the other components of the center. Genotyping
is done using standard commercially available primers for short tandem
repeat-based markers and fluorescence-based screening.
Principal Investigator: Ken
During the first five years of the center, beginning
in 1997, we accomplished the following highlights for Core C:
- Completed over 350,000 successful genotypes.
- Over 7000 DNA samples prepared, indexed and stored.
- Implemented the Discovery Manager Database.
- Development of preamplification method permitting genotyping of buccal
- Apparently successful first test of the SNP chip from Affymetrix.