Faculty Fellows

James M. Sikela

Department of Pharmacology
University of Colorado at Denver
and Health Sciences Center
PO Box 6511, Mail Stop 8303
Aurora, CO 80045

Phone:(303) 724-3385
Fax: (303) 724-3663
Email:
James.Sikela@uchsc.edu
Website
Recent Publications

Research Interests:

Specific areas of interest include the genetic factors involved in learning and memory, and alcohol and drug abuse and the use of evolutionary genomics approaches to identify the genes unique to the human lineage.

Publication Highlights:

1. Popesco M.C., MacLaren E.J., Hopkins J., Dumas L., Cox M., Meltesen L., McGavran L., Wyckoff G.J., and Sikela J.M.. Human Lineage-Specific Amplification, Selection, and Neuronal Expression of DUF1220 Domains. Science 313: 1304-1307, 2006. (Abstract)  (Full Text Article)

2. Dumas, L., Kim, Y.H., Karimpour-Fard, A., Cox, M., Hopkins, J., Pollack, J.R., and Sikela, J.M.: Gene copy number variation spanning 60 million years of human and primate evolution. Genome Research, 17:1266-1277, 2007. | pubmed abstract |

3. Sikela J.M. The Jewels of Our Genome: The Search for the Genomic Changes Underlying the Evolutionarily Unique Capacities of the Human Brain. PLoS Genet 2(5): e80, 2006. | pubmed abstract |