The use of genetic strategies to identify the underlying biological bases for the behavioral and physiological actions of drugs of abuse with special emphasis on nicotine.
Selected Publications:
1. Stitzel JA. (2008) Naturally occurring genetic variability in the nicotinic acetylcholine receptor alpha4 and alpha7 subunit genes and phenotypic diversity in humans and mice. Frontiers in bioscience, 13, 477-91. | pubmed abstract |
2. Mexal S, Jenkins PM, Lautner MA, Iacob E, Crouch EL, Stitzel JA.(2007). alpha7 nicotinic receptor gene promoter polymorphisms in inbred mice affect expression in a cell type-specific fashion. The Journal of biological chemistry, 282(18), 13220-7. | pubmed abstract |
3. Butt CM, King NM, Stitzel JA, Collins AC.(2004) Interaction of the nicotinic cholinergic system with ethanol withdrawal. The Journal of pharmacology and experimental therapeutics, 308(2), 591-9. | pubmed abstract |